Our findings suggest that P-SF3B1 engages with the upper loop of the U6-ISL element, likely contributing to the stabilization of the RNA structures required for splicing catalysis
Next day membranes were washed 3 10 min in PBS-T and incubated for 1 h in 5% low-fat milk in PBS-T with appropriate secondary antibody
Jain P, Kanagal-Shamanna R, Zhang S, Ahmed M, Ghorab A, Zhang L, Ok CY, Li S, Hagemeister F, Zeng D, Gong T, Chen W, Badillo M, Nomie K, Fayad L, Medeiros LJ, Neelapu S, Fowler N, Romaguera J, Champlin R, Wang L , Wang ML
Endoplasmic reticulum is an important intracellular organelle that carries out multiple physiological functions such as protein folding, posttranslational modifications, biosynthesis of fatty acids and sterols, detoxification of xenobiotics and the storage of intracellular calcium 53
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